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Natural Active Immunity
Naturally Passive Immunity
Artificially Active Immunity
Artificially Passive Immunity
Adoptive Immunity
1.Considered the “best” form to have, “but there’s a catch”: Naturally Active Immunity
2. Associated with breast feeding and colostrums: Naturally Passive Immunity
3. Associated with IgG placental transfer inuter: Naturally Passive Immunity
4. Associated with genetically engineered Hepatitis B surface antigen vaccination: Artificially Active Immunity.
5. Associated with Hepatitis B immune globulin (HBIg) shot given post needle stick injury in a non vaccinated individual: Artificially Passive Immunity
6. Concept of stem cell or bone marrow transplants: Adoptive Immunity
7. Getting a real infection and recovering: Naturally active Immunity
8. Associated with people with non-functioning immune systems: Artificially active Immunity
9. Polio vaccine and DPT are examples of this type: artificially active immunity
10. Giving injections of pooled ab typically from animal/human sources to treat exposures to various natural toxins is called artificially passive Immunity
Part Two
11. Penicillin allergy falls into this type: Type I
12. Poison ivy sensitivity falls into this type: Type II
13. TB skin tests or PPD falls into this type: Type III
14. Hemolytic Transfusion reactions falls into this type: Type IV
15. HDN, Hemolyitc Disease of the New Born falls into this type: Type III
16. Bee sting allergy falls into this type: Type I
17. IgE antibody is involved with this type: Type I
18. This reaction is Tc mediated: Type IV
19. SLE falls into this type: Type III
20. The use of epinephrine (epi pen) may be used for severe forms of this type: Type I
Part Three
a. classical pathwa
b. alternate pathway
c. both of the above
d. neither of the above
27. AHG stand for anti human globulin and is usually made in an animal model and is specific for binding normally to a FAB portion of human antibody.
a. True
b. False
29. The DAT looks for ab coated cells that occurred invivo
30. .CRP tests often have postzone problems causing false negatives.
31.CRP has which of the following properties
32.Prozone is ______and results in a false____
33.To show a significant ab titer one can demonstrate a
34. The normal ratio of CD4 to CD8 is 1:2 but is often reversed in HIV patients with AIDS.
a. True
b. False
35 . A significant titer is
36. C3b has the following properties
a. Can activate the classical complement pathway
b. produced in the kidney
c. levels rise 1000X in dayys and because of this has postzone problems
d. can act like an opsonin
e. all of the above
37. Two dilutions differences is the same as four fold
A. True
b. False
38.Conjugates are best defined as
a. when two substances are joined to make an indicator or visualizing substance to show ag and ab reactions
b. AHG tagged with Enzyme
c. AHG tagged with FITC
d. AHG tagged with I 125
e. all of the above are true
39.Zone of equivalence are ______and results in a____
a. too much ab , false negative
b. too much ab , false positive
c.too much ag , false neg
d. to much ag , false positive
e.correct concentration of ag and ab, visible reactions
40.What is the dilution in tube 10 in a serial 10 tube dilution using 50ul of patient sample and 50ul of diluent in each tube.
41 : In serologic testing on a patient with a hypothetical disease, the following results were obtained
a) acute specimen titer 1.8
b) post specimen titer 1.32
Your best conclusion would be
a. Inconclusive, the results do not show a fold rise
b. Repeat the test with another specimen to see if a 1:128 or four fold increase occurs
c. Conclusive the patient has a four fold rise
d. Negative result, the titer is too low to be significant
e. To check with Wayne for a consult (not the right answer)
42: An adjuvant is best defined as
a. an allergen
b. a substance that causes a heterophile response to a carrier protein
c. a substance that will react with antibody but is not capable of stimulating it alone.
d. a substance that allows for the slow release of an antigen to provide a greater and more sustained immunologic response.